Dual‐phase imaging of cardiac metabolism using hyperpolarized pyruvate

Purpose Previous cardiac imaging studies using hyperpolarized (HP) [1‐ 13 C]pyruvate were acquired at end‐diastole (ED). Little is known about the interaction between cardiac cycle and metabolite content in the myocardium. In this study, we compared images of HP pyruvate and products at end‐systole (ES) and ED. Methods A dual‐phase 13 C MRI sequence was implemented to acquire two sequential HP images within a single cardiac cycle at ES and ED...