The emerging role of immune checkpoint inhibitors for the treatment of breast cancer

Introduction Breast cancer has traditionally been viewed as immunogenically ‘cold,’ but two immune checkpoint inhibitors have been approved in combination with chemotherapy for PD-L1 positive advanced triple-negative breast cancer (TNBC), and pembrolizumab was also recently approved for early stage TNBC. As the landscape is rapidly evolving, a comprehensive review of checkpoint inhibitors in breast cancer is needed to aid clinicians in selecting...