Cytotoxicity of aptamer-conjugated chitosan encapsulated mycogenic gold nanoparticles in human lung cancer cells

The present work investigated the cytotoxicity of aptamer (Apt)-conjugated chitosan (CST) encapsulated mycogenic (Talaromyces purpureogenus (Tp)) gold nanoparticles (AuNPs) in human lung cancer cell line. A total of three steps were involved in the fabrication of Apt-CST-Tp-AuNPs: (i) mycogenic synthesis of Tp-AuNPs using mycelial extract of T. purpureogenus, (ii) encapsulation of the chitosan on Tp-AuNPs (CST-Tp-AuNPs), and (iii) conjugation of...