Anti-fungal activity and preliminary active components separation from ethanol extracts in Saffron (Crocus sativus L.) lateral buds

Published on Dec 1, 2021in Industrial Crops and Products5.645
· DOI :10.1016/J.INDCROP.2021.114081
Defu Wang4
Estimated H-index: 4
(Shanxi Agricultural University),
Cui Liyan3
Estimated H-index: 3
(Shanxi Agricultural University)
+ 3 AuthorsYanbing Niu4
Estimated H-index: 4
(Shanxi Agricultural University)
Abstract null null Saffron (Crocus sativus L.) is renowned for the active compounds contained in its stigmas, which are used in traditional medicine and as a spice. However, although the stigmas are well above the average yield, the lateral buds of saffron are usually discarded in saffron culturing. In order to expand saffron resource utilization, this study assessed the anti-fungal activities of saffron lateral bud ethanol extracts on six common food-borne pathogenic fungi, as well as investigated the stability of these activities under various heat and pH conditions. Furthermore, the active anti-fungal components of ethyl acetate phase were preliminarily separated by silica gel column chromatography technology and its major chemical constituents were investigated by HPLC-MS/MS. Results revealed that the ethyl acetate phase of saffron lateral bud ethanol extracts elicited a remarkable anti-fungal effect against the tested fungi, especially Aspergillus niger (83.47 %) and Trichoderma viride (79.93 %). Moreover, these inhibitory effects were stable in neutral and acidic pH ranges at temperatures
#1Federica Scicutella (UniFI: University of Florence)H-Index: 1
#2Federica Mannelli (UniFI: University of Florence)H-Index: 7
Last. Arianna Buccioni (UniFI: University of Florence)H-Index: 22
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For decades antibiotics have been used in poultry rearing to support high levels of production. Nevertheless, several problems have arisen because of the misuse of antibiotics (i.e., antibiotic resistance, residues in animal products, environmental pollution). Thus, the European Union (EU) as well as the European Food Safety Authority (EFSA) promote action plans to diminish the use of antibiotics in animal production. Alternatives to antibiotics have been studied. Polyphenols (PPs) or organic ac...
#8Reena Singh (LPU: Lovely Professional University)H-Index: 4
The ingestion of contaminated water and food is known to cause food illness. Moreover, on assessing the patients suffering from foodborne disease has revealed the role of microbes in such diseases. Concerning which different methods have been developed for protecting food from microbes, the treatment of food with chemicals has been reported to exhibit an unwanted organoleptic effect while also affecting the nutritional value of food. Owing to these challenges, the demand for natural food preserv...
#3Amit Kumar (Central University of Punjab)H-Index: 35
Abstract Background Infectious diseases are the leading cause of death in 21st century due to antimicrobial resistance and scarcity of new molecules to undertake rising infections. There could be a multiple reasons behind antimicrobial resistance whether it is increased drug metabolism or bacterial endotoxins. The demand of effective medication is increasing day by day to treat microbial infections and combat antimicrobial resistance. In recent years most of the synthetic antimicrobials develope...
Saffron (Crocus sativus L.) has been traditionally used in food preparation and as a medicinal plant. It currently has numerous therapeutic properties attributed to it, such as protection against ischemia, as well as anticonvulsant, antidepressant, anxiolytic, hypolipidemic, anti-atherogenic, anti-hypertensive, antidiabetic, and anti-cancer properties. In addition, saffron has remarkable beneficial properties, such as anti-apoptotic, anti-inflammatory and antioxidant activities, due to its main ...
#2Maria Eleni Grafakou (UoA: National and Kapodistrian University of Athens)H-Index: 1
OBJECTIVES: To prepare a lyophilized saffron aqueous extract (SFE) and determine its chemical profile and serum and tissue pharmacokinetics after intravenous and oral administration to C57/Bl6J mice. METHODS: Lyophilized SFE was prepared, characterized using semi-preparative HPLC and NMR analysis, and stability studies at room temperature, and was quantified for crocin content with an HPLC-PDA method. After intravenous and oral administration of SFE (60 mg/kg, reconstituted with water for inject...
#1Samad Ghaffari (Tabriz University of Medical Sciences)H-Index: 17
#2Neda Roshanravan (Tabriz University of Medical Sciences)H-Index: 13
Abstract Objective Saffron as a natural product has long been used to impede and treat different disorders including cardiovascular disease (CVDs). Stigma is the most principal part of saffron. Various compounds such as carotenoids and flavonoids are the essential components of saffron stigma. The health benefits of saffron have been shown in previous studies; however, there is a lack of comprehensive data on the mechanistic aspects of its cardiovascular-health properties. This current comprehen...
#1Radu Claudiu Fierascu (University of Agronomic Sciences and Veterinary Medicine of Bucharest)H-Index: 18
#2Alina Ortan (University of Agronomic Sciences and Veterinary Medicine of Bucharest)H-Index: 15
Last. Irina Fierascu (University of Agronomic Sciences and Veterinary Medicine of Bucharest)H-Index: 14
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Plants in general (and herbs in particular) possess several compounds with very good antioxidant activity (such as phenolic acids, flavonoids, terpenes, carotenoids, and proanthocyanidins). The natural compounds responsible for the antioxidant activity also have other important biological activities, thus the use of antioxidant natural products is constantly encouraged by the scientific community, as well as by the general desire for healthy and natural food that shifted the industry to the expl...
#1Azar Hosseini (MUMS: Mashhad University of Medical Sciences)H-Index: 15
#2Bibi Marjan Razavi (MUMS: Mashhad University of Medical Sciences)H-Index: 28
Last. Hossein Hosseinzadeh (MUMS: Mashhad University of Medical Sciences)H-Index: 81
view all 3 authors...
: Saffron petal is the main by-product of saffron processing which produced at high level but it is not applied and thrown out. Saffron petal is containing of several compounds such as mineral agents, anthocyanins, flavonoids, glycosides, alkaloids and kaempferol. As saffron petal is cheaper and produces in large amounts compared to saffron stigma, so, it can be considered as an appropriate source for different purposes. In this review different pharmacological properties of saffron petal such a...
#2Bin Yang (Peking Union Medical College)H-Index: 9
The dried stigma of Crocus sativus (saffron) is a world&s precious spice and traditional medicine possessing plenty of pharmacological effects. Because the stigma represents only 7.4% of total weight of the fresh flower, when the stigma is separated from the flowers, large quantities of floral bio-residues are discarded. Accordingly, the utilization of the non-medicinal parts of saffron has drawn people&s attention. Studies showed that the non-medicinal parts of saffron were rich in flavonoids, ...
Roscoea procera Wall. is one of the important Himalayan medicinal plant used in traditional as well as in modern health care system. The present study aimed to find out the influence of different phenophases on the phenolic compounds and anti-oxidant properties by analysing after every week for over 4 months from shoot bud initiation to the preparation of senescence. Concentration of total phenolic content were found to be about 1.5 times higher in preparation of senescence phase (6.10 mg GAE/g ...
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