Molecular implications of HOX genes targeting multiple signaling pathways in cancer
Abstract
Homeobox (HOX) genes encode highly conserved homeotic transcription factors that play a crucial role in organogenesis and tissue homeostasis. Their deregulation impacts the function of several regulatory molecules contributing to tumor initiation and progression. A functional bridge exists between altered gene expression of individual HOX genes and tumorigenesis. This review focuses on how deregulation in the HOX-associated signaling pathways...
Paper Details
Title
Molecular implications of HOX genes targeting multiple signaling pathways in cancer
Published Date
Oct 6, 2021
Journal
Volume
38
Issue
1
Pages
1 - 30
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