Inhibition of SARS-CoV-2 polymerase by nucleotide analogs from a single-molecule perspective
Abstract
The absence of 'shovel-ready' anti-coronavirus drugs during vaccine development has exceedingly worsened the SARS-CoV-2 pandemic. Furthermore, new vaccine-resistant variants and coronavirus outbreaks may occur in the near future, and we must be ready to face this possibility. However, efficient antiviral drugs are still lacking to this day, due to our poor understanding of the mode of incorporation and mechanism of action of nucleotides analogs...
Paper Details
Title
Inhibition of SARS-CoV-2 polymerase by nucleotide analogs from a single-molecule perspective
Published Date
Oct 7, 2021
Journal
Volume
10
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Notes
History