Factors Regulating the Activity of LINE1 Retrotransposons

Genes3.50
Volume: 12, Issue: 10, Pages: 1562 - 1562
Published: Sep 30, 2021
Abstract
LINE-1 (L1) is a class of autonomous mobile genetic elements that form somatic mosaicisms in various tissues of the organism. The activity of L1 retrotransposons is strictly controlled by many factors in somatic and germ cells at all stages of ontogenesis. Alteration of L1 activity was noted in a number of diseases: in neuropsychiatric and autoimmune diseases, as well as in various forms of cancer. Altered activity of L1 retrotransposons for...
Paper Details
Title
Factors Regulating the Activity of LINE1 Retrotransposons
Published Date
Sep 30, 2021
Journal
Volume
12
Issue
10
Pages
1562 - 1562
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