Heat shock protein vaccines in glioblastoma

Pages: 39 - 53
Published: Jan 1, 2022
Abstract
Heat shock proteins (HSPs) are cellular chaperones abundant in mammalian cells, and play an important role in response to stressors such as hyperthermia, hypoxia, and oxidative stress. The peptide-binding property of HSPs, together with their ability to deliver antigens to antigen-presenting cells, makes them a target for modulation in cancer immunotherapy. As a result, an autologous, patient-derived HSP-96 peptide complex vaccine (HSPPC-96) has...
Paper Details
Title
Heat shock protein vaccines in glioblastoma
Published Date
Jan 1, 2022
Journal
Pages
39 - 53
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