Effect of combined stabilizers on midazolam nanosuspension properties
Abstract
Poorly soluble drugs are often a challenging problem in drug formulation. Midazolam is considered one of the best first-line drugs in managing status epilepticus in children who require emergency drug treatment. Owing to poor water solubility, however, oral bioavailability of midazolam is relatively low and insufficient. To improve its dissolution and absorption, nanosuspensions of midazolam hydrochloride were formulated with different...
Paper Details
Title
Effect of combined stabilizers on midazolam nanosuspension properties
Published Date
Sep 20, 2021
Journal
Volume
31
Issue
2
Pages
215 - 222
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