Serum Metabolome Mediates the Antiobesity Effect of Celastrol-Induced Gut Microbial Alterations

Volume: 20, Issue: 10, Pages: 4840 - 4851
Published: Sep 16, 2021
Abstract
The antiobesity effect of celastrol has been reported in numerous studies, but the underlying mechanism remains unclear. It is widely accepted that gut dysbiosis is closely related to obesity. The potential effect of celastrol on microbiota is worth exploring. In this study, the celastrol-induced weight loss was validated in high-fat diet (HFD)-induced obese mice, with the detection of reported phenotypes including a reduction in food intake,...
Paper Details
Title
Serum Metabolome Mediates the Antiobesity Effect of Celastrol-Induced Gut Microbial Alterations
Published Date
Sep 16, 2021
Volume
20
Issue
10
Pages
4840 - 4851
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