Intensive care unit

Premature rupture of membranes

Obstetrics

Preeclampsia

Fetus

Infectious disease (medical specialty)

Disease

Coronavirus disease 2019 (COVID-19)

Biology

Pandemic

Intensive care medicine

Extracorporeal membrane oxygenation

Internal medicine

Immunology

Pregnancy

Genetics

Medicine

American Journal of Obstetrics and Gynecology

Physiological, mechanical, and immunologic alterations in pregnancy could potentially affect the susceptibility to and the severity of COVID-19 during pregnancy. Owing to the lack of comparable incidence data and the challenges with disentangling differences in the susceptibility from different exposure risks, the data are insufficient to determine whether pregnancy increases the susceptibility to SARS-CoV-2 infection. The data support pregnancy as a risk factor for severe disease associated with COVID-19; some of the best evidence comes from the United States Centers for Disease Control and Prevention COVID-19 surveillance system, which reported that pregnant persons were more likely to be admitted to an intensive care unit, require invasive ventilation, require extracorporeal membrane oxygenation, and die than nonpregnant women of reproductive age.

An update on COVID-19 and pregnancy