New anti-pulmonary fibrosis prenylflavonoid glycosides from Epimedium koreanum

Four new prenylflavonoid glycosides, namely koreanoside H–K (1–4), together with eleven known ones (5–15) were isolated from the leaves of Epimedium koreanum Nakai. Their structures were elucidated by 1D NMR, 2D NMR, HR-ESI-MS, IR and UV. The identification of the sugar moieties was carried out by means of acid hydrolysis and HPLC analysis of their derivatives. It is worth noting that compound 3 and compound 4 were elucidated to contain fucose...