The suitability of high throughput automated patch clamp for physiological applications

Published: Oct 8, 2021
Abstract
Although automated patch clamp (APC) devices have been around for many years and have become an integral part of many aspects of drug discovery, high throughput instruments with gigaohm seal data quality are relatively new. Experiments where a large number of compounds are screened against ion channels are ideally suited to high throughput APC, particularly when the amount of compound available is low. Here we evaluate different APC approaches...
Paper Details
Title
The suitability of high throughput automated patch clamp for physiological applications
Published Date
Oct 8, 2021
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