Dependence receptors: new targets for cancer therapy

Volume: 13, Issue: 11
Published: Sep 20, 2021
Abstract
Dependence receptors are known to promote survival and positive signaling such as proliferation, migration, and differentiation when activated, but to actively trigger apoptosis when unbound to their ligand. Their abnormal regulation was shown to be an important feature of tumorigenesis, allowing cancer cells to escape apoptosis triggered by these receptors while promoting in parallel major aspects of tumorigenesis such as proliferation,...
Paper Details
Title
Dependence receptors: new targets for cancer therapy
Published Date
Sep 20, 2021
Volume
13
Issue
11
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