Deconstructing progressive inflammatory fibrosis in recessive dystrophic epidermolysis bullosa

Volume: 13, Issue: 10
Published: Sep 13, 2021
Abstract
Recessive dystrophic epidermolysis bullosa (RDEB) is an inherited blistering skin disease, resulting from biallelic mutations in COL7A1, the gene encoding type VII collagen (C7). At mucocutaneous barriers, tissue integrity relies upon linked extracellular matrix (ECM) proteins forming a physiologic suture, connecting basal epidermal keratinocytes to the underlying dermis. C7 secreted from epidermal keratinocytes and dermal fibroblasts...
Paper Details
Title
Deconstructing progressive inflammatory fibrosis in recessive dystrophic epidermolysis bullosa
Published Date
Sep 13, 2021
Volume
13
Issue
10
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