P041 Tandem mass tag-based quantitative proteomic profiling identifies novel putative serum biomarkers for the diagnosis of drug-induced liver injury in patients

Published: Sep 1, 2021
Abstract

Background

Diagnosis of drug-induced liver injury (DILI) remains a significant challenge in interventional clinical trials during drug development and in clinical practice. We aimed to discover novel diagnostic biomarkers using proteomics and to evaluate their performance characteristics in distinguishing DILI from acute and chronic liver injury from other etiologies.

Methods

Adults with idiosyncratic DILI and acute non-DILI...
Paper Details
Title
P041 Tandem mass tag-based quantitative proteomic profiling identifies novel putative serum biomarkers for the diagnosis of drug-induced liver injury in patients
Published Date
Sep 1, 2021
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