Clinical significance of coexisting histological diffuse type in stage II/III gastric cancer

Since 1965, the Laurén classification has been used most commonly for gastric adenocarcinoma, with two main types: intestinal type and diffuse type. Signet ring cell carcinoma (Sig) and non‑solid poorly differentiated adenocarcinoma (Por2) are the histological forms of diffuse type that are often found in advanced tumors, and they seem to be associated with a poor prognosis. S‑1‑based adjuvant chemotherapy for patients with stage II/III gastric...