Multi-omics reveals the positive leverage of plant secondary metabolites on the gut microbiota in a non-model mammal

Flavonoids are important plant secondary metabolites (PSMs) that have been widely used for their health-promoting effects. However, little is known about overall flavonoid metabolism and the interactive effects between flavonoids and the gut microbiota. The flavonoid-rich bamboo and the giant panda provide an ideal system to bridge this gap.Here, integrating metabolomic and metagenomic approaches, and in vitro culture experiment, we identified...