Freeze-dried vs spray-dried nanoplex DPIs based on chitosan and its derivatives conjugated with hyaluronic acid for tuberculosis: In vitro aerodynamic and in silico deposition profiles
Abstract
• Dry powder inhalers were developed for drug the delivery using nanotechnology. • Nanoparticles were synthesized using hyaluronic acid along with chitosan. • Also, hyaluronic acid was used with chitosan derivatives to prepare nanoparticles. • Spray-drying and freeze-drying were used as drying techniques to obtain nanopowders. • Stochastic lung model exhibited particle deposition in the lungs. • Drying techniques show small changes in sample...
Paper Details
Title
Freeze-dried vs spray-dried nanoplex DPIs based on chitosan and its derivatives conjugated with hyaluronic acid for tuberculosis: In vitro aerodynamic and in silico deposition profiles
Published Date
Nov 1, 2021
Journal
Volume
160
Pages
110775 - 110775
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