Comparison of the clinical features in open and closed format intensive care units: A systematic review and meta-analysis

The difference in clinical outcomes between closed and open designs of intensive care units (ICUs) is still an open question.We conducted a systematic review and meta-analysis to compare total mortality, hospital and ICU length of stay (LOS) and mortality as primary outcomes, and severity of illness based on physiological variables, organ failure assessment, age, duration of mechanical ventilation and ventilator-associated pneumonia frequency as...