Viral Manipulation of a Mechanoresponsive Signaling Axis Disassembles Processing Bodies

Volume: 41, Issue: 11
Published: Oct 26, 2021
Abstract
Processing bodies (PBs) are ribonucleoprotein granules important for cytokine mRNA decay that are targeted for disassembly by many viruses. Kaposi's sarcoma-associated herpesvirus is the etiological agent of the inflammatory endothelial cancer, Kaposi's sarcoma, and a PB-regulating virus. The virus encodes kaposin B (KapB), which induces actin stress fibers (SFs) and cell spindling as well as PB disassembly. We now show that KapB-mediated PB...
Paper Details
Title
Viral Manipulation of a Mechanoresponsive Signaling Axis Disassembles Processing Bodies
Published Date
Oct 26, 2021
Volume
41
Issue
11
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