Single-cell analyses of human pancreas: characteristics of two populations of acinar cells in chronic pancreatitis

Volume: 321, Issue: 5, Pages: G449 - G460
Published: Nov 1, 2021
Abstract
We conducted single cell RNA sequencing on pancreas tissue from five individuals. We identified eleven unique cell clusters including a large population of dedifferentiated cells as well as two unique clusters of acinar cells, one of which appears to exist in a transitional state. We also examined the cellular response of pancreas tissue to stimulation and identified affected genes and pathways, including pancreatic digestive...
Paper Details
Title
Single-cell analyses of human pancreas: characteristics of two populations of acinar cells in chronic pancreatitis
Published Date
Nov 1, 2021
Journal
Volume
321
Issue
5
Pages
G449 - G460
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