Wnt signaling promotes tumor development in part through phosphofructokinase 1 platelet isoform upregulation
Abstract
The activation of Wnt signaling has been detected in various types of human cancer and has been shown to be associated with cancer development. In the present study, it was revealed that Wnt signaling induced the expression of phosphofructokinase 1 platelet isoform (PFKP), which has been reported to catalyze a rate‑limiting reaction in glycolysis and is important for the Warburg effect, proliferation, colony formation and cancer cell migration....
Paper Details
Title
Wnt signaling promotes tumor development in part through phosphofructokinase 1 platelet isoform upregulation
Published Date
Sep 10, 2021
Journal
Volume
46
Issue
5
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