Comparative assessment of genes driving cancer and somatic evolution.

Published: Aug 31, 2021
Abstract
Genetic alterations of somatic cells can drive non-malignant clone formation and promote cancer initiation. However, the link between these processes remains unclear hampering our understanding of tissue homeostasis and cancer development. Here we collect a literature-based repertoire of 3355 well-known or predicted drivers of cancer and noncancer somatic evolution in 122 cancer types and 12 noncancer tissues. Mapping the alterations of these...
Paper Details
Title
Comparative assessment of genes driving cancer and somatic evolution.
Published Date
Aug 31, 2021
Journal
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