Influence of Extracellular Matrix on Elastin Biosynthesis

The process of cellular differentiation is guided by molecular controls that regulate the expression of cell-specific genes. Clearly, these controls must be precise in both their specificity and temporal appearance. The signals that direct the molecular regulation of differentiation are intrinsic and extrinsic (extracellular) factors. Intrinsic mechanisms require a change in activity (e.g., by molecular modification) or concentration (by...