Intestinal chemosensitivity in irritable bowel syndrome associates with small intestinal TRPV channel expression

Volume: 54, Issue: 9, Pages: 1179 - 1192
Published: Sep 2, 2021
Abstract
Irritable bowel syndrome (IBS) patients often experience meal-associated symptoms. However, the underlying mechanisms are unclear.To determine small intestinal mechanisms of lipid-induced symptoms and rectal hypersensitivity in IBS METHODS: We recruited 26 IBS patients (12 IBS-C, 14 IBS-D) and 15 healthy volunteers (HV). In vivo permeability was assessed using saccharide excretion assay. Rectal sensitivity was assessed using a barostat before...
Paper Details
Title
Intestinal chemosensitivity in irritable bowel syndrome associates with small intestinal TRPV channel expression
Published Date
Sep 2, 2021
Volume
54
Issue
9
Pages
1179 - 1192
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