Efficacy and Safety of Vibrating Capsule for Functional Constipation: A Randomized, Double-Blind, Placebo-Controlled, Multicenter Trial

Background: Functional constipation (FC) is an intractable disease that carries large financial burden as well as emotional and physical stress. We aimed to assess the efficacy and safety of the newly developed smartphone-controlled vibrating capsule (VC) in patients with FC. Methods: This was a multicenter, blinded, placebo-controlled randomized trial in six top general hospitals in China focusing on patients aged 18 to 80 with FC. Patients...