Age-associated changes in microglia and astrocytes ameliorate blood-brain barrier dysfunction
Abstract
Blood-brain barrier (BBB) dysfunction is associated with an accumulation of neurotoxic molecules and increased infiltration of peripheral cells within the brain parenchyma. Accruing evidence suggests that microglia and astrocytes play a crucial role in the recovery of BBB integrity and the corralling of infiltrating cells into clusters after brain damage, but the mechanisms involved remain unclear. Intriguingly, the results of flow cytometry and...
Paper Details
Title
Age-associated changes in microglia and astrocytes ameliorate blood-brain barrier dysfunction
Published Date
Dec 1, 2021
Volume
26
Pages
970 - 986
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