Human Induced Pluripotent Stem Cell-Derived Macrophages Ameliorate Liver Fibrosis
Abstract
With an increasing number of patients with degenerative hepatic diseases, such as liver fibrosis, and a limited supply of donor organs, there is an unmet need for therapies that can repair or regenerate damaged liver tissue. Treatment with macrophages that are capable of phagocytosis and anti-inflammatory activities such as secretion of matrix metalloproteinases (MMPs) provide an attractive cellular therapy approach. Human induced pluripotent...
Paper Details
Title
Human Induced Pluripotent Stem Cell-Derived Macrophages Ameliorate Liver Fibrosis
Published Date
Oct 1, 2021
Journal
Volume
39
Issue
12
Pages
1701 - 1717
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Notes
History