Zinc trafficking 1. Probing the roles of proteome, metallothionein, and glutathione

Volume: 13, Issue: 10
Published: Sep 2, 2021
Abstract
The cellular trafficking pathways that conduct zinc to its sites of binding in functional proteins remain largely unspecified. In this study, the hypothesis was investigated that nonspecific proteomic binding sites serve as intermediates in zinc trafficking. Proteome from pig kidney LLC-PK1 cells contains a large concentration of such sites, displaying an average conditional stability constant of 1010-11, that are dependent on sulfhydryl ligands...
Paper Details
Title
Zinc trafficking 1. Probing the roles of proteome, metallothionein, and glutathione
Published Date
Sep 2, 2021
Volume
13
Issue
10
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