Genetic characteristics and response to systemic therapies of acral lentiginous melanoma at a tertiary care center—a retrospective review

Acral lentiginous melanoma (ALM) is an aggressive subtype of cutaneous malignant melanomas that accounts for 50-80% of melanomas in ethnic minorities. Studies on the genetic profile of these tumors largely result from cohorts in Europe, Asia, and Latin America, few inclusive of Black patients.We aim to describe the clinicopathological and genetic characteristics in a diverse cohort of ALM patients.A retrospective analysis of 93 patients with a...