Role of enteric glial cells in the toxicity of phycotoxins: Investigation with a tri-culture intestinal cell model
Abstract
• New intestinal relevant tri-culture cell model was developed. • Phycotoxins showed different toxicity on the Caco-2/HT29-MTX/EGC cells tri-culture. • OA decreased viability and integrity of Caco-2/HT29-MTX cell; induced IL-8 release. • EGC reinforced integrity and reduced inflammatory response following OA exposure. • The toxin PTX2 induced some modifications of EGC morphology. Lipophilic phycotoxins are secondary metabolites produced by...
Paper Details
Title
Role of enteric glial cells in the toxicity of phycotoxins: Investigation with a tri-culture intestinal cell model
Published Date
Oct 1, 2021
Journal
Volume
351
Pages
89 - 98
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Notes
History