Concentrated collagen hydrogels: A new approach for developing artificial tissues

Collagen's unique properties are ideal for creating tissue and organ equivalents. Rapid development of methods for creating such objects has revealed that collagen biomaterials have poor mechanical properties, which complicates their use. A potential solution is increasing the collagen concentration in the initial solution; however, there is little data on the behavior of cells cultured inside concentrated collagen hydrogels for an extended...