An automated ASPECTS method with atlas-based segmentation

• An automated ASPECTS method with atlas-based segmentation is proposed. • The performance of different parameters and thresholds are evaluated and compared. • Brain density shift is better for quantitative analysis of early ischemic changes. • The accuracy of proposed method achieves 80% on the test set. As a simple and reliable systematic method to evaluate the early ischemic changes in the blood supply region of the middle cerebral artery of...