Upregulation of Mir342 in Diet-Induced Obesity Mouse and the Hypothalamic Appetite Control
Abstract
In obesity and type 2 diabetes, numerous genes are differentially expressed, and microRNAs are involved in transcriptional regulation of target mRNAs, but miRNAs critically involved in the appetite control are not known. Here, we identified upregulation of miR-342-3p and its host gene Evl in brain and adipose tissues in C57BL/6 mice fed with high fat-high sucrose (HFHS) chow by RNA sequencing. Mir342 (-/-) mice fed with HFHS chow were protected...
Paper Details
Title
Upregulation of Mir342 in Diet-Induced Obesity Mouse and the Hypothalamic Appetite Control
Published Date
Aug 30, 2021
Journal
Volume
12
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