Integrative analysis of the gut microbiome and metabolome in a rat model with stress induced irritable bowel syndrome
Abstract
Stress is one of the major causes of irritable bowel syndrome (IBS), which is well-known for perturbing the microbiome and exacerbating IBS-associated symptoms. However, changes in the gut microbiome and metabolome in response to colorectal distention (CRD), combined with restraint stress (RS) administration, remains unclear. In this study, CRD and RS stress were used to construct an IBS rat model. The 16S rRNA gene sequencing was used to...
Paper Details
Title
Integrative analysis of the gut microbiome and metabolome in a rat model with stress induced irritable bowel syndrome
Published Date
Sep 2, 2021
Journal
Volume
11
Issue
1
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