Biofabrication of functional protein nanoparticles through simple His-tag engineering

Volume: 9, Issue: 36, Pages: 12341 - 12354
Published: Aug 30, 2021
Abstract
We have developed a simple, robust, and fully transversal approach for the a-la-carte fabrication of functional multimeric nanoparticles with potential biomedical applications, validated here by a set of diverse and unrelated polypeptides. The proposed concept is based on the controlled coordination between Zn2+ ions and His residues in His-tagged proteins. This approach results in a spontaneous and reproducible protein assembly as nanoscale...
Paper Details
Title
Biofabrication of functional protein nanoparticles through simple His-tag engineering
Published Date
Aug 30, 2021
Volume
9
Issue
36
Pages
12341 - 12354
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