Movement disorders in patients with Rett syndrome: A systematic review of evidence and associated clinical considerations

This systematic review identified and thematically appraised clinical evidence of movement disorders in patients with Rett syndrome (RTT).Using PRISMA criteria, six electronic databases were searched from inception to April 2021. A thematic analysis was then undertaken on the extracted data to identify potential themes.Following the thematic analysis, six themes emerged: (i) clinical features of abnormal movement behaviors; (ii) mutational...