The shared genetic architecture between epidemiological and behavioral traits with lung cancer
Abstract
The complex polygenic nature of lung cancer is not fully characterized. Our study seeks to identify novel phenotypes associated with lung cancer using cross-trait linkage disequilibrium score regression (LDSR). We measured pairwise genetic correlation (rg) and SNP heritability (h2) between 347 traits and lung cancer risk using genome-wide association study summary statistics from the UKBB and OncoArray consortium. Further, we conducted analysis...
Paper Details
Title
The shared genetic architecture between epidemiological and behavioral traits with lung cancer
Published Date
Sep 2, 2021
Journal
Volume
11
Issue
1
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