Multiple malignant tumors in a patient with familial chordoma, a case report
Abstract
Background Chordoma is a rare bone tumor that is typically resistant to chemotherapy and is associated with genetic abnormalities of the T-box transcription factor T ( TBXT ) gene, which encodes the transcription factor brachyury. Brachyury is felt to be a major contributor to the development of chordomas. Case presentation We describe a 67-year-old woman who developed an undifferentiated pleomorphic sarcoma in her thigh. Despite treatment with...
Paper Details
Title
Multiple malignant tumors in a patient with familial chordoma, a case report
Published Date
Aug 31, 2021
Journal
Volume
14
Issue
1
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