Disrupted NOS2 metabolism drives myoblast response to wasting-associated cytokines
Abstract
Skeletal muscle wasting drives negative clinical outcomes and is associated with a spectrum of pathologies including cancer. Cancer cachexia is a multi-factorial syndrome that encompasses skeletal muscle wasting and remains understudied, despite being a frequent and serious co-morbidity. Deviation from the homeostatic balance between breakdown and regeneration leads to muscle wasting disorders, such as cancer cachexia. Muscle stem cells (MuSCs)...
Paper Details
Title
Disrupted NOS2 metabolism drives myoblast response to wasting-associated cytokines
Published Date
Oct 1, 2021
Journal
Volume
407
Issue
1
Pages
112779 - 112779
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