Skin Resident Memory T Cells May Play Critical Role in Delayed-Type Drug Hypersensitivity Reactions
Abstract
Delayed-type drug hypersensitivity reactions (dtDHR) are immune-mediated reactions with skin and visceral manifestations ranging from mild to severe. Clinical care is negatively impacted by a limited understanding of disease pathogenesis. Though T cells are believed to orchestrate disease, the type of T cell and the location and mechanism of T cell activation remain unknown. Resident memory T cells (TRM) are a unique T cell population...
Paper Details
Title
Skin Resident Memory T Cells May Play Critical Role in Delayed-Type Drug Hypersensitivity Reactions
Published Date
Aug 23, 2021
Journal
Volume
12
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