Proteomic basis of modulation of post ischemic fibrosis by MSC exosomes

Abstract
Following an ischemic event, there is activation of fibroblasts leading to scar formation. It is critical to limit the pro-fibrotic remodeling and activate the reparative, remodeling phase to limit cardiac diastolic dysfunction. Mesenchymal stem cell (MSC) exosomes offer significant protection against ischemia-related systolic dysfunction. Here we studied if MSC exosomes would offer protection against pro-fibrotic events in mouse hearts...
Paper Details
Title
Proteomic basis of modulation of post ischemic fibrosis by MSC exosomes
Published Date
Aug 25, 2021
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