Tumour fatty acid metabolism in the context of therapy resistance and obesity
Abstract
Fatty acid metabolism is known to support tumorigenesis and disease progression as well as treatment resistance through enhanced lipid synthesis, storage and catabolism. More recently, the role of membrane fatty acid composition, for example, ratios of saturated, monounsaturated and polyunsaturated fatty acids, in promoting cell survival while limiting lipotoxicity and ferroptosis has been increasingly appreciated. Alongside these insights, it...
Paper Details
Title
Tumour fatty acid metabolism in the context of therapy resistance and obesity
Published Date
Aug 20, 2021
Journal
Volume
21
Issue
12
Pages
753 - 766
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Notes
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