The transcription factor ZEB1 regulates stem cell self-renewal and cell fate in the adult hippocampus
Abstract
Radial glia-like (RGL) stem cells persist in the adult mammalian hippocampus, where they generate new neurons and astrocytes throughout life. The process of adult neurogenesis is well documented, but cell-autonomous factors regulating neuronal and astroglial differentiation are incompletely understood. Here, we evaluate the functions of the transcription factor zinc-finger E-box binding homeobox 1 (ZEB1) in adult hippocampal RGL cells using a...
Paper Details
Title
The transcription factor ZEB1 regulates stem cell self-renewal and cell fate in the adult hippocampus
Published Date
Aug 1, 2021
Journal
Volume
36
Issue
8
Pages
109588 - 109588
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