Proteome heterogeneity and malignancy detection in pancreatic cyst fluids

Pancreatic cyst neoplasms (PCNs), such as intraductal papillary mucinous neoplasms (IPMNs) and mucinous cystic neoplasms (MCNs), represent one of the main dysplastic precursor lesions that could give rise to invasive pancreatic carcinoma.1, 2 While guidelines have been suggested to assist in the diagnosis and management of PCNs, including resection and surveillance recommendations,3, 4 clinical management of cyst lesions remains imprecise due to...