A novel multi-functionalized multicellular nanodelivery system for non-small cell lung cancer photochemotherapy

A red blood cell membrane (RBCm)-derived drug delivery system allows prolonged circulation of an antitumor treatment and overcomes the issue of accelerated blood clearance induced by PEGylation. However, RBCm-derived drug delivery systems are limited by low drug-loading capacities and the lack of tumor-targeting ability. Thus, new designs of RBCm-based delivery systems are needed.Herein, we designed hyaluronic acid (HA)-hybridized RBCm...