TIPE2 inhibits PDGF-BB-induced phenotype switching in airway smooth muscle cells through the PI3K/Akt signaling pathway

Volume: 22, Issue: 1
Published: Aug 26, 2021
Abstract
Childhood asthma is a common respiratory disease characterized by airway inflammation. Tumor necrosis factor-α-induced protein 8-like 2 (TIPE2) has been found to be involved in the progression of asthma. This study aimed to explore the role of TIPE2 in the regulation of airway smooth muscle cells (ASMCs), which are one of the main effector cells in the development of asthma.ASMCs were transfected with pcDNA3.0-TIPE2 or si-TIPE2 for 48 h and then...
Paper Details
Title
TIPE2 inhibits PDGF-BB-induced phenotype switching in airway smooth muscle cells through the PI3K/Akt signaling pathway
Published Date
Aug 26, 2021
Volume
22
Issue
1
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