Novel glutamic acid derivatives from the bulbs of Fritillaria verticillate Willd and their antitumor activities
Abstract
Four previously undescribed glutamic acid derivatives, verticillamines A-D (1-4), together with six known compounds (5-10) were isolated from the bulbs of Fritillaria verticillate Willd. The structures of (1-10) were established on the basis of UV, IR, MS, 1D and 2D NMR, and the absolute configurations of compounds (1-4) were determined by calculated ECD methods. Among them, compounds (1-3) were rare 2-methyl-γ-lactam alkaloid derivatives....
Paper Details
Title
Novel glutamic acid derivatives from the bulbs of Fritillaria verticillate Willd and their antitumor activities
Published Date
Oct 1, 2021
Journal
Volume
154
Pages
105022 - 105022
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