Functionalization of C(sp3)-H bonds adjacent to heterocycles catalyzed by earth abundant transition metals

The inception of C–H bond functionalization of common organic substrates has markedly restructured the retrosynthesis of complex molecules. Among the many classes of C–H bonds, those next to a heteroaromatic ring are exceptionally distinct given the fact that their reactivity are controlled either by coordinating the heteroatom to a transition metal catalyst or by the electronic influences of the ring or both during the C–H cleavage process....